Why Alzheimer's Disease Is More Common In Women
Medical providers have long known that more women contract Alzheimer's disease (AD) than men. Until recently, many attributed this difference to female longevity. However, recent research has shown that multiple biological and social factors make women more vulnerable to AD. It's not just a matter of women living longer. By age 65, 1 in 5 women has Alzheimer's, while only 1 in 11 men has the condition. Biology Makes Women More Vulnerable to AD 1. Apolipoprotein E Lipid biology is an essential factor in how AD impacts women more than men. The human body produces four Apolipoproteins (apoE1, apoE2, apoE3, and apoE4) that play a significant role in Alzheimer's disease. The most interesting protein of the four is apoE4. People with genes that code for apoE4 are more likely to contract Alzheimer's late in life. However, women with the apoE4 gene are more prone to AD than men with the same gene. Female apoE4 carriers are twice as likely to develop Alzheimer's as wom...